VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University
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Research Simulation
Determination of genes governed by
a bacteriophage regulatory factor

Time: Wed, Thu, Mon June 14 - June 19, 9:00 am - 11:30
Place: Bioinformatics Computer Core Lab (Rm 104), Life Sciences Bldg
Organizers: Gail Christie and Jeff Elhai
Audience: Primarily 1st year students

Scenario 1 (phage)         Scenario 2 (Blast)

Schedule
Wed June 14, 9am
Identification of NucC-regulated genes in Serratia marcescens (Background)
Notes           Presentation
Thu June 15, 9am Computational search for gene sequences:
The truth about Blast
- Link: National Center for Biotech Information
- Link: Serratia marcescens Db11 genome site
- Tour: Computational search for gene
            sequences

- Notes: Alignment of pairs of sequences
- Questionnaire
- Worksheet: Smith-Waterman worksheet
- Summary: Smith-Waterman rules
Mon June 19, 9am Experiments with a Visible BlastN
- Notes/Problem set: Data aggregates
- Notes: The Visible BlastN
- Notes: Blast scoring
- Questionnaire: (coming)

Late breaking news!

Billy Budd presents:
Regulation of the Serratia marcescens extracellular nuclease: positive control by a homolog of P2 Ogr encoded by a cryptic prophage.
Jin S, Chen Y, Christie GE, Benedik MJ (1996).
J Molec Biol 256:264-278.

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