VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University
imageimageHomeBio What?The InstituteThe People
The Institute
Goals of the Institute
Two-year plan
Class Web pages
News
Archives
Applying to the Institute
About BBSI
image

Research Simulation Scenario
Phage sequences in bacterial genomes
Spreading the tools of death

A silent army of phage 933W siblings
In addition to prophage 933W, the EHEC strain EDL933 carries at least 13 cryptic prophages (prophages that have lost some essential phage function so that they can no longer grow as phages). Seven of these cryptic prophages (CPs) contain tail fiber gene sequences with significant similarity to the tail fiber gene of phage 933W, especially at their 3' ends, but also significant differences.

Can these genes serve as a reservoir of variant tail fiber sequences that might expand the host range of phage 933W?


 

Back to main Scenario page      back one page     continue