VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University
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Research Simulation
Genes Determining Plant-Cyanobacterial Symbioses/Blast

Time: Wed June 3, 9:00 am - 11:30 am
          Thu June 4, 9:00 am - 11:30 am
          Tue June 9, 9:00 am - 11:30 am
Place: Bioinformatics Computer Core Lab (Rm 104), Life Sciences Bldg
Organizers: Wan-Ling Chiu, Jeff Elhai
Audience: Primarily 1st year students

Schedule
 Wed June 3, 9am
Rationale for transcript sequencing
- The value of plant/cyanobacterial symbioses
- Sequencing to find symbiosis-specific genes
Resource: The Issues of Nitrogen
      (from the International Nitrogen Initiative)
 Thu June 4, 9am The Nature of Blast
Link: National Center for Biotech Info
Link: BioBIKE portal
Mystery #1: Do sharks have blood?
Mystery #2: Anthrax attack or not?
Resource: DG29 sequence (for Mystery #2)
Presentation: Analysis of cDNA library
 Tue June 9, 9am The Nature of Blast (part 2)
(Before coming please read notes and answer questionnaire)
Notes: Blast: Alignment of pairs of sequences
Resource: Persemlidis A, Fondon III JW (2001).
  Having a BLAST with bioinformatics
  (and avoiding BLASTphemy)
.
  Genome Biol 2:reviews2002.1 - 2002.10
Questionnaire
 
Jonathan Levin presents:
Yano K et al (2008). CYCLOPS, a mediator of symbiotic intracellular accommodation. Proc Natl Acad Sci USA 105:20540-20545.
Erick Breathwaite presents: ???
Gherbi H et al (2008). SymRK defines a common genetic basis for plant root endosymbioses with arbuscular mycorrhiza fungi, rhizobia and Frankia bacteria. Proc Natl Acad Sci USA 105:4928-4932.

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