VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University
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Research Simulation Scenario
Mathematical and Computer Simulation Models:
Theory & Application

ParaSys, Inc is a company founded on the use of gene sequencing to develop the metabolome of the parasite T. cruzi, the causative agent in Chagas disease. You decide to make a mathematical model of the MAPK cascade signaling pathway as a first attempt at trying to understand the dynamics of the host parasite interaction. The MAPK or mitogen-activated protein kinase cascade is illustrated in the above figure.  Now what?

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