Mathematical and Computer Simulation Models: Theory & Application
Scenario3 - Infectious Disease
Infectious diseases, in spite of antibiotic and other
treatments, remain one of the biggest medical problems to date. The overall
problem of understanding host-parasite dynamics is extremely important, as it
is intrinsic to the study of infection at
all organismal scales. Many examples
of such host-parasite systems exist, with debilitating and/or fatal
consequences for humans all over the planet; malaria, schistosomiasis, and
Chagas’ Disease, for example. Epidemiologically, it is estimated that around 2
billion people are estimated to harbor STH and schistosomiasis worms.
Morbidity
estimates are that 300 million individuals are severely ill with worms, of
which 50% are school-age children. Mortality estimates, for Africa alone, find
that the death toll due to schistosomiasis may be as high as 200,000 per year.
Despite recent advances in the control of Chagas’ disease, millions of Latin
Americans and numerous US citizens remain at risk for infection with the T.
cruzi parasite, the causal agent in Chagas’ disease.
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