Save money by spending electrons

Bioinformatics has come to the rescue. Using the known properties of the glycolytic enzymes of T. brucei, two researchers from the University of Bath and the University of Marseille — Robert Eisenthal and Athel Cornish-Bowden — have created a computer simulation of the metabolism of the parasite. With this model in hand, they systematically considered the effect of inhibiting different parts of the glycolytic pathway to determine what effect this would have on ATP production, hence growth of the parasite.

(See Eisenthal & Cornish-Bowden, 1998)

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