VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University

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Melanie Smith

  Home Institution
  Cedar Crest College
  Allentown, Pennsylvania
  E-mail: mjsmith@cedarcrest.edu

  Home mentor
Richard Kliman
  E-mail: rmkliman@cedarcrest.edu

VCU Lab
Massey Cancer Center Addition
Department of Medicinal Chemistry
Tel: (804)628-1956

VCU mentor
Brad Windle
Massey Cancer Center Addition Rm. 319
bwindle@VCU.edu

 

Summer 2006
Research Proposal

Identification of Cell Function Pathways of Genes from 60 Human Cell Lines Using Neural Networks and Random Forests

Research article, presented (June 29, 2006)

Functional Discovery via a Compendium of Expression Profiles
- Hughes et. al. 2000. Cell. 102: 109-126.

Research presentation (8 August 2006)
3rd Annual VCU-BBSI Closing Symposium

Discovery of Cell Function Pathway�Associations Based on Neural Network and Random Forest Models

Academic Year 2006-2007
Research Proposal

Cancer Studies Using Bioinformatic Techniques

Research Proposal Links

Pathway Networks

Pathway Probabilities

Pathway Association Scores

Summer 2007
Summit on Systems Biology Poster

Cellular Pathway Mapping Using Gene Expression Profiles and Upstream Elements

Research article, presented (6 July 2007)

Why are Rhesus Macaques Resistant to HIV-1?
What About the Rest of Us?


-Paper: Kaiser, S., H. Malik, and M. Emerman. 2007. Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science. 316: 1756-1758.

Research article, presented (27 July 2007)

Emerging Principles of Regulatory Evolution


-Paper: Prud'homme, B., N. Gompel, and S. Carroll. 2007. Emerging principles of regulatory evolution. The national academy of sciences. 104: 8605-8612.

Research presentation (10 July 2007)

Cellular Pathway Mapping Using Gene Expression Profiles and Upstream Elements

Final Report

Cellular Pathway Networking Using Gene Expression Profiles and Transcription Factor Binding Sites

Final Report Links

Gene IDs and TFBS Data Part 1

Gene IDs and TFBS Data Part 2

Pathway Probabilities

Confusion Matrix

TFBS Importance Values

TFBS Gene Ontology

 

Prior research
- KL(phi)1 Bacteriophage, Creating a Southern Blot Probe
- Alchemy and the Black Plague: A Sociocultural Perspective

Characteristic interests and activities
Drive-in Movies
Painting
Photography
Forensics
The Dynamics of Genomes

Home mentor's research interests
Evolutionary Genetics
- Codon usage and base composition among various organisms
- Population genetics and the development of new species
- Conservation/Ecological genetics of the queen conch

My favorite research articles
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Last updated 2006 � May 17th

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